In neonatal mammals, arginine is synthesized in the enterocyte, with either proline or glutamate as the dietary precursor. We have shown several times in piglets that proline is the only precursor ...

According to the study authors, the findings suggest that having more arginine in the blood and unusually high activation of the urea cycle may drive colorectal cancer in young people. They say ...

Pegargiminase is a PEGylated therapeutic protein based on a microbial enzyme, arginine deiminase (ADI). It converts extracellular arginine into citrulline, thus blocking the external supply of ...