The DNA damage response is a network of cellular pathways that sense, signal and repair DNA lesions. Surveillance proteins that monitor DNA integrity can activate cell cycle checkpoints and DNA ...

Genotoxic stressors, including oxidative stress, inflammation, and environmental factors are closely intertwined processes that significantly contribute to ...

Most people associate sunburns with DNA damage -- it's what we've been taught in textbooks and by dermatologists for years.

"Understanding how different cancer cells react to DNA damage could ... measure a cell's response to damaged DNA at the single-cell level and observed a new pathway to the activation of NF-κB.

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response ... cells react to DNA damage could lead to ...

"Understanding how different cancer cells react to DNA damage could ... measure a cell's response to damaged DNA at the single-cell level and observed a new pathway to the activation of NF-κB.

This is important because some forms of cell death are unnoticed by the immune system, while others trigger an immune response ... "The DNA inside our cells is constantly experiencing damage ...

This extension builds on a 2024 agreement to define and discover biomarkers within the DNA damage response (DDR) biological space to predict the clinical benefit of one or more drugs in Debiopharm ...