Department of Microbiology and Cell Biology, Indian Institute of Science, C.V. Raman Avenue, Bangalore 560012, India ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

Total RNA was extracted using the hot phenol method. The RNA was further purified with two phenol‐chloroform treatments and then treated with RQ1 DNase (Promega, Madison, WI) to remove possible DNA ...