Here, the authors report thiazolyl ketone inhibitors of cPLA2α starting from compound GK470 (AVX235), and the discovery of a more potent and selective lead, GK420 (AVX420), with significant ...

Various Ways Generative AI Impacts Drug Discovery in the Healthcare Sector Generative AI is considered the subset of AI (Artificial Intelligence) and unlocks fruitful opportunities in the drug ...

Yet, a century ago, its discovery by Edwin Hubble opened humanity's eyes as to how large the universe really is, and revealed that our Milky Way galaxy is just one of hundreds of billions of ...

Haisheng Zhang, founder and CEO of Signet Therapeutics. “This milestone validates the transformative power of integrating organoid and AI technologies to propel the entire drug discovery process—from ...

A coalition of public defenders and other groups introduced itself on Monday to urge Albany lawmakers to leave in place, undisturbed, recent discovery reforms. Coined the “Alliance to Protect ...

Harry Sumnall receives funding from public grant awarding bodies for alcohol and other drugs research, and fees from (international) not-for-profit organisations and government departments for ...

The hope is that using AI for the drug discovery part of that process could cut the time and cost, and result in more success. A new era, where AI is at the centre of the drug discovery process is ...

Upstream Process Development (UPD) is essential to ensure robust, scalable processes that can efficiently bring biotherapeutics to market. However, challenges such as optimizing yield, ensuring ...

MIT’s new AI model predicts antibody structures with greater accuracy, aiding disease treatment and streamlining drug discovery. With this model ... Identifying a variety of good candidates early in ...