1 Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA 2 ...

Aging is an inevitable progressive decline in physiological organ function that increases the chance of disease and death. The renin–angiotensin system (RAS) is involved in the regulation of ...

There are several traditional model systems commonly used to study cancer, including cell culture based, zebrafish and mouse models. These models all have their own unique advantages and limitations ...

familial acute respiratory distress syndrome, ANLN-related, dog (MONDO:1012930) neuromuscular channelopathy, KCNG1-related, cattle (MONDO:1012911) progressive retinal atrophy, FAM161A-related, dog ...

p27 (also known as KIP1, and encoded by CDKN1B) is regulated by multiple signal transduction pathways in normal and malignant cells. CDKN1B transcription can be regulated by the FoxO family and ...

Atrial fibrillation (AF) is the most common cardiac arrhythmia with a massive burden on global health. The prevalence of AF increases dramatically with age and can be up to 18% in patients older than ...