Fibroblasts are the most common cell type in connective tissue. They can be compared to 'nature's stitches', holding together ...

We found that these Thbs4-positive astrocytes modulate the dense extracellular matrix at the lesion border by both synthesizing and degrading hyaluronan. We also show that while the accumulation of ...

Aberrant expressions of matrix proteins by cancer-associated fibroblasts (CAFs) alter the mechanical properties of the tumor extracellular matrix (ECM). This results in increased ECM desmoplasia and ...

Transgenic mouse models of Marfan syndrome exposed a surprising and crucial function of elastic extracellular matrix components in regulating TGFβ signalling. By interacting with unprocessed ...

PRNewswire Billerbeck [Germany] January 23 MedSkin Solutions Dr Suwelack AG is pleased to announce the publication of a new ...

A drop in estradiol and progesterone levels after menopause could increase cartilage aging and degeneration, leading to ...

Keloids are fibrotic scars that extend beyond the boundaries of the original wound, often causing physical disfigurement and ...

Neutrophil extracellular trap (NET) formation is increased in SLE and has been proposed ... Results The putative role of NET-externalised matrix metalloproteinases (MMPs) in altering the functional ...

AMSBIO has introduced MatriMix for PDX, a fully defined extracellular matrix (ECM) hydrogel specifically formulated to ...

Researchers have identified the key role of vitamin D and the enzyme CYP24A1 in keloid scar development, offering a promising ...

Methods: In this study, poly (caprolactone) (PCL) nanofibers, PCL nanofibers uniformly coated with the extracellular matrix derived from endothelial cells (ECd), and bi-directional linear gradient ECd ...