Researchers at Leipzig University’s Faculty of Medicine and Shandong University in China have discovered a new mechanism that ...

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

Septerna has a market cap of $750mn and $130mn in cash and ST investments. Discover SEPN's groundbreaking drug discovery ...

Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology ...

Announcing a new article publication for BIO Integration journal. Diabetes, a common metabolic condition, poses a substantial health burden worldwide. To revolutionize diabetes management, enhance ...

EPFL researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced ...

More information: The current publication was produced as part of Collaborative Research Centre 1423, Structural Dynamics of GPCR Activation and Signaling, which is funded by the German Research ...

Researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel drug ...

Figure 3. Heatmap of the dysregulated genes involved mitochondria dysfunction in space. One of the dysregulated pathways that is not in Figure 2 is G-protein coupled receptor (GPCR) signaling, which ...