Grade 2 gliomas are still considered low-grade. Surgery is generally the first treatment and in some cases, it can even be curative. Certain patients are considered high-risk for recurrence after ...

Pediatric low-grade gliomas (pLGGs) are a group of tumors that affect children, teenagers, and young adults. They are the most common tumors of the brain and spinal cord in young people.

In summary, we demonstrate the development of a novel alveolar organoid model and use it to identify effectors of SFTPC maturation necessary for AT2 health. Disorders of surfactant protein biology ...

This marks a significant milestone as SIGX1094 is the first pipeline drug discovered using AI and organoid disease model to enter clinical trials, and the first targeted therapy candidate to ...

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract that affects an estimated 2.4 to 3.1 million people in the US alone. Despite decades of research, ...

High-grade gliomas (HGGs), characterized by their high malignancy, remain challenging to treat despite standard treatment regimens, including surgery, radiotherapy, chemotherapy, and tumor treating ...

Gliomas account for almost 80% of primary malignant brain tumors, and they result in more years of life lost than do any other tumors. Glioblastoma, the most common type of glioma, is associated ...

They grow rapidly and can spread to areas near the original tumor and to other areas in the brain. Astrocytomas are the most common type of glioma, accounting for about half of all childhood brain ...