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Department of Biotechnology & Enzyme Catalysis, Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str., 4, 17487 Greifswald, Germany ...

Macrocyclic natural products have evolved to fulfil numerous biochemical functions, and their pharmacological properties have led to their development as drugs. The current set of more than 100 ...

Carboxylic acids have been shown to be good phosphate bioisosteres (Burke and Lee, 2003; Elliott et al., 2012). Yet phosphonic acids could potentially better-replicate cognate TOP1-DNA substrate ...

E. coli JM109 and plasmid pPIC9K were used for gene cloning and propagation procedures. P. pastoris GS115 was used as a host for the expression of recombinant hPH20 and its mutants. PrimeSTAR Max DNA ...

Nearly a century of innovation and vision: that’s what it takes to be the University of Oklahoma. And it’s what makes the University of Oklahoma's Michael F. Price College of Business #1 in Oklahoma, ...