The study presents compelling evidence that the melanocortin system originating in the arcuate nucleus of the hypothalamus plays a crucial role in puberty onset, representing a significant advance in ...

Hunger is an ancestral and evolutionary survival instinct; its importance is evident in the complex and redundant pathways involving all five senses that regulate it. 1,2 Historically, when humans ...

Alcohol also suppresses pro-opiomelanocortin (POMC) neurons, a type of cell in the hypothalamus which reduce appetite, caused by the decrease in leptin and insulin (as mentioned above). On the ...

To investigate the hypothalamus as a potential key target of 17α-estradiol’s effects on life ... ukb-e-30800_CSA). Interestingly, QRFP, IGF1, AGRP, TAC4, GRP, CLU, BNF, PCSK7, PACAP, ANP, TAC3, CRH, ...

The hypothalamus is the main area in the brain ... there are orexigenic coexpressing neuropeptide Y/Agouti gene-related protein (NPY/AgRP) and anorexigenic pro-opiomelanocortin (POMC)/cocaine ...

4,5 These ghrelin-containing neurons send efferent fibers to neurons that contain neuropeptide Y (NPY) and agouti-related protein (AgRP)—NPY/AgRP neurons—and might stimulate the release of ...