12.299. Image Credit: Sino Biological Inc. Immobilized MMAE-ADC at 1 μg/mL (100 μL/well) can bind the Anti-MMAE Antibody, the EC₅₀ of Anti-MMAE is 50 -1000 ng/mL. The naked antibody (without ...
IPH4502 differentiated topoisomerase I inhibitor payload supports its potential in patients with tumors resistant to MMAE-ADC. The Phase 1, open-label, multi-center study, includes a Part 1 Dose ...