Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Select the journal/section where you want your idea to be submitted: This Research Topic is the second volume of the “The Role of Monocytes/Macrophages in Autoimmunity and Autoinflammation” Community ...

2 Its specificity for RA is thus limited. Here we describe the mRNA and protein expression of PAD enzymes in monocytes and macrophages, as well as in synovial fluid mononuclear cells (SFMCs). Possible ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical studies have implicated macrophage-mediated immune tolerance. Hence, pathways ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

It was recently shown that monocyte/macrophage infiltration into the liver upon injury is critically regulated by the CCL2/CCR2 axis and is functionally important for perpetuating hepatic inflammation ...

1 Non-Coding RNA and Cancer Biology Laboratory, Department of Zoology, Central University of Punjab, Bathinda, India 2 Amity Centre for Translational Research, Amity University, Noida, India ...

AIMS This study was undertaken to confirm the distribution and expression of the molecule CD44 on human corneas under normal and pathological conditions. METHODS Fifty eight corneal buttons from adult ...

Monocytopenia describes a low number of monocytes, a type of white blood cell. Monocytes are made in the bone marrow and account for 2% to 6% of white blood cells at any given time. They work ...

The paper illustrates a valuable approach to generating TCR transgenic mice specific for known epitopes. Solid evidence validates the described pipeline for identification of TCRs from single-cell ...

2024年12月，中山大学医学院张旭东、侯琳琳教授团队在期刊【Nano Today】上发表题为“In situ engineering of mRNA-CAR T cells using spleen ...