Federal officials on Thursday approved a new type of pain pill designed to eliminate the risks of addiction and overdose ...

More information: Kyoungjune Pak et al, Anorexia nervosa is associated with higher brain mu-opioid receptor availability, Molecular Psychiatry (2025). DOI: 10.1038/s41380-025-02888-3 Provided by ...

Summary: Elevated opioid neurotransmission in the brain may underlie appetite loss and emotional symptoms in anorexia ... fear to gain weight, and a distorted body image. Mu-opioid receptor (MOR) ...

Transdermal fentanyl may be used for patients who do not tolerate the orally available opioids or who cannot ... equivalent daily dose of 50 mg of oral morphine. [9] Because it can take up to ...

The company tested cebranopadol, a dual nociceptin/orphanin FQ peptide (NOP) receptor and µ-opioid peptide (MOP) receptor agonist, in a late-stage trial on patients who have undergone cosmetic ...

Tris Pharma reported positive Phase III data Wednesday for its non-opioid painkiller, cebranopadol, showing strong efficacy as well as a solid safety profile. The New Jersey–based company tested the ...

Certain proteins found in the human brain have long been known to be critical to controlling how brain cells communicate with each other. So-called GABA A receptors are proteins that control the ...

Attempting to reduce fatal opioid overdoses and encourage more people to seek treatment, fire department paramedics in Kitsap County will start administering the medication buprenorphine in the ...

The treatment of severe pain with opioids has thus far been limited by their unwanted central side effects. Recent research promises new approaches, including opioid analgesics acting outside the ...

Behavioral addictive disorders (BADs) have become a significant societal challenge over time. The central feature of BADs is the loss of control over engaging in and continuing behaviors, even when ...