Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...

This valuable work examines the role of the oxidoreductase MftG in Mycolicibacerium smegmatis alcohol metabolism. A solid set of data is presented to show that, in the context of ethanol metabolism, ...

Oxidoreductases are enzymes that catalyze transfer of electrons ... as cofactors. The name of the oxidoreductase generally takes the form of '[acceptor name] dehydrogenase'. Structural and ...

This study by Graca et al. explores ethanol metabolism pathways in mycobacteria. The enzyme, MftG, a flavoprotein dehydrogenase, is shown to act as an electron shuttle between an uncommon redox ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. A machine learning-based drug screening technique has been developed and optimized ...

School of Physics and Astronomy, University of Leeds, Leeds LS2 9JT, U.K. School of Physics and Astronomy, University of Leeds, Leeds LS2 9JT, U.K. Astbury Centre for Structural Molecular Biology, ...

Elevated liver enzymes can occur for many reasons. Most often, elevated liver enzymes are temporary and resolve on their own without treatment. Occasionally, elevated liver enzymes require additional ...

CCM Biosciences has developed groundbreaking compounds that activate the enzyme SIRT3, potentially reversing age-related cellular decline. These first-in-class drugs outperform existing treatments and ...

This enzyme could be transformative for industry, it not only speeds up a crucial class of chemical transformation, but does so with remarkable precision, even when working with challenging chemical ...

Temperature affects enzyme-catalysed reactions by influencing the rate at which they occur. For a reaction to occur between an enzyme and substrate the two molecules need to collide. At lower ...

There were also no new safety signals and safety data were consistent with the known safety profile of the treatment. Vatiquinone is a small molecule inhibitor of the oxidoreductase enzyme ...

Enzymatic activity of the electron transport system via the MTT assay is a colorimetric assay where NAD (P) H-dependent cellular oxidoreductase enzymes reflect the number of viable cells. •ATP content ...