Zebrafish with this mutation had poorly developed eye cells, weaker responses to light, and changes in the normal structure of their retinas. These tiny, tropical fish are used as a tool to find ...

A new research paper was published in Volume 16 of Genes & Cancer on January 20, 2025, entitled, "Analysis of pathogenic variants in retinoblastoma reveals a potential gain of function mutation." ...

The work also provides fundamental insights into the earliest genes that are required to control the development of the eye. This European research consortium identified a mutation in the miR-204 gene ...