"These findings illuminate a critical mechanism that connects local synaptic activity to the broader gene expression changes necessary for learning and memory," said Mark Dell'Acqua, professor of ...

The international team describes their results and the underlying molecular mechanism in Cell Metabolism. Ergothioneine is a natural compound found in certain fungi such as oyster or shiitake ...

Today, Canada alongside other G7 RRM members (European Union, France, Germany, Italy, Japan, the United Kingdom, the United States) as well as G7 RRM Observer states (Australia, Netherlands, New ...

This manuscript from Clayton and co-authors aims to clarify the molecular mechanism of BRAF dimer selectivity. Indeed, first generation BRAF inhibitors, targeting monomeric BRAFV600E, are ineffective ...

Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, United States Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of ...