We investigated whether mutations in the PRSS1 gene are associated with hereditary and non-hereditary pancreatitis. As a modifier role has been proposed for trypsin inhibitor (serine protease ...

More than 67,000 Americans will be diagnosed with pancreatic cancer this year. Learn more about the disease and how PanCAN can help.

This material on this page is ©2025 American Society of Clinical Oncology, all rights reserved. Licensing available upon request. For more information, please ...

This material on this page is ©2025 American Society of Clinical Oncology, all rights reserved. Licensing available upon request. For more information, please ...

Pancreatic cancer can cause back pain that spreads from the abdomen. It often affects the middle of the back and may feel like a dull ache. For some people, the pain may come and go. Pancreatic ...

7, 2025 — Pancreatic cancer patients may benefit ... in patients with lung cancer treated with immune checkpoint ... Inhibitor Drugs to Treat Aggressive Breast Cancer Identified Feb.

Several protein kinases are deregulated and overexpressed in human cancers and are thus attractive targets for selective pharmacologic inhibitors. In pancreatic cancer, many tyrosine kinases were ...

Chemoradiation is considered a reasonable treatment option for patients with locally advanced, unresectable pancreatic cancer ... (EGF receptor tyrosine kinase inhibitor) and capecitabine ...

For harvesting or subculturing, cells were detached using trypsin–EDTA (PAA Laboratories ... Cells were preincubated for 2 h with the inhibitors before stimulation with FFA. According to the ...

The pancreas is a key player in glucose homeostasis, but the occurrence of newly diagnosed DM after acute pancreatitis (AP), the most frequent disease of the pancreas, has never been assessed ...