A meta-analysis by the National Kidney Foundation found that individuals who produced 2 to 2.5 litres of urine daily were 50 ...

Uricase degrades relatively insoluble uric acid to the more soluble compound allantoin. Urate reabsorption by urate transporter-1 is partly suppressed at the proximal tubule lumen membrane by the ...

Uric acid is a waste product found in urine. If your body makes too much or doesn't eliminate enough of it, uric acid levels can become too high—a condition known as hyperuricemia. High uric acid ...

The process of breaking down purines (found in various foods) by the body results in the production of uric acid as a waste product. If the levels of this acid in your bloodstream become excessive ...

Sign of High Uric Acid Levels: Frequent urination, also known as polyuria, is a serious health problem that mainly affects people above 40. While a constant urge to urinate is often linked to ...

Diabetes-related premature mortality is largely preventable and reversible if identified and managed early. Accordingly, we intend to investigate the predictive value of uric acid to albumin ratio ...

High uric acid causes painful gout diseases like kidney stones. Recognising early symptoms can be a preventive measure against that. Tap to read top warning signs on hands.

Nephrolithiasis is diagnosed by ultrasound ... (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), serum creatinine (SCr) and uric acid ...

Eating a high purine diet can increase the risk of hyperuricemia, while a low purine diet helps minimize the number of purines in the body and reduce the amount of uric acid in the blood.

In addition, XRx-225 is a pre-clinical stage program for Type 2 Diabetic Nephropathy. XORTX is working to advance its clinical development stage products that target aberrant purine metabolism and ...