复旦大学附属中山医院等多单位的研究人员 Linnan Li、Hao Cheng 等人在《Cell Death Discovery》期刊上发表了题为 “METTL3 regulates autophagy of hypoxia - induced cardiomyocytes by targeting ATG7” 的论文。该研究揭示了 METTL3 ...

From being a promising yet underexplored approach in the 1990s, mRNA therapeutics have evolved dramatically. The discovery of ...

Instead they end in a conserved stem–loop that interacts with stem–loop binding protein (SLBP), a factor involved in several steps of histone mRNA metabolism: pre-mRNA processing, translation ...

拷贝数改变在三阴性乳腺癌患者中经常发生。在这里，作者确定了FAD合成酶（FLAD1）在TNBC中作用的拷贝数扩增，并从机制上证明了这种扩增通过FLAD1/LSD1/SREBP1轴增加脂质代谢来驱动肿瘤发生。

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But the bill also would prohibit mRNA vaccines, like those developed by Pfizer and Moderna to combat COVID-19, Shippy told the Idaho Statesman. Vaccines that use mRNA technology are not gene ...

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Riboswitches are RNA sensors that allow bacteria to sense and respond to their environment. Here, Bushhouse et al. demonstrate that the sensitivity of several riboswitches can be tuned by ...