The Clean Development Mechanism (CDM), defined in Article 12 of the Protocol, allows a country with an emission-reduction or emission-limitation commitment under the Kyoto Protocol (Annex B Party) to ...

This is a well-written manuscript on the mechanism of the DFG flip in kinases. This conformational change is important for the toggling of kinases between active (DFG-in) and inactive (DFG-out) states ...

Guangdong Provincial Key Laboratory of Chiral Molecule and Drug Discovery, State Key Laboratory of Anti-Infective Drug Discovery and Development, School of Pharmaceutical Sciences, Sun Yat-sen ...

There’s a precedent for combining the two checkpoint inhibitor mechanisms in HCC, as Bristol-Myers Squibb claimed FDA approval last month for the combination of its PD-1 drug Opdivo (nivolumab ...

The emergence of '-omics' technologies capable of yielding deep molecular profiles of cancer genomes has enabled the elucidation of somatic genetic alterations associated with resistance to ...

Effeeda, the trademark name for fenquinotrione, is a novel active ingredient and triketone herbicide with HPPD inhibitor mechanism of action discovered by Kumiai. It is a herbicide effective against a ...

This can include: being rude saying things that aren’t appropriate (for example, that someone is overweight) talking to strangers undressing in public apparent loss of sexual inhibition (for example, ...