Endopeptidase or endoproteinase are proteolytic peptidases that break peptide bonds of nonterminal amino acids (i.e. within the molecule), in contrast to exopeptidases, which break peptide bonds from end-pieces of terminal amino acids. [1]

An endopeptidase is a proteolytic enzyme that cleaves a peptide bond within a peptide or protein sequence but not at the termini. From: Encyclopedia of Cell Biology, 2016

Endopeptidases, also known as proteases, cleave peptide bonds within the interior of a protein molecule, resulting in the formation of smaller peptide fragments. They play a crucial role in protein digestion and are responsible for breaking down …

endopeptidase or proteinase a type of PROTEASE (protein-splitting enzyme) that hydrolyses peptide bonds between particular amino acids located inside the chain, but not at the ends. There are three major endopeptidases in the mammalian gut: PEPSIN (stomach); TRYPSIN and CHYMOTRYPSIN (pancreas).

Peptidases are enzymes capable of cleaving, and thereby often inactivating, small peptides. They are widely distributed on the surface of many different cell types, with the catalytic site exposed only at the external surface.

The meaning of ENDOPEPTIDASE is any of a group of enzymes that hydrolyze peptide bonds within the long chains of protein molecules : protease.

Endopeptidase: An enzyme that catalyzes the cleavage of peptide bonds within a polypeptide or protein. Peptidase refers to the fact that it acts on peptide bonds and endopeptidase refers to the fact that these are internal bonds.

In the stomach, protein materials are attacked initially by a gastric endopeptidase known as pepsin. When the protein material is passed to the small intestine, proteins, which are only partially digested in the stomach, are further attacked …

Endopeptidases employ various catalytic mechanisms; within this group are the aspartic endopeptidases, cysteine endopeptidases, glutamic endopeptidases, metalloendopeptidases, serine endopeptidases, and threonine endopeptidases. The term oligopeptidase is reserved for those enzymes that act specifically on peptides.

All of the enzymes that hydrolyse peptide bonds are now known as peptidases, and these are divided into the exopeptidases and the endopeptidases.