Piperine, possibly along with its isomer chavicine, [2] is the compound [3] responsible for the pungency of black pepper and long pepper. It has been used in some forms of traditional medicine . [ 4 ]

2021年9月1日 · Piperine, found in black pepper, has been shown to have positive health effects. BioPerine, a piperine extract found in supplements, may help improve nutrient absorption and blood sugar levels ...

2023年10月4日 · What is Piperine? Piperine is the alkaloid responsible for the pungency of black pepper. This bioactive compound is also found in other pepper species. Piperine has been used in traditional medicine for centuries, particularly in Ayurvedic practices, for its ability to enhance digestion and promote gastrointestinal functionality. Benefits of ...

Piperine is a N-acylpiperidine that is piperidine substituted by a (1E,3E)-1-(1,3-benzodioxol-5-yl)-5-oxopenta-1,3-dien-5-yl group at the nitrogen atom. It is an alkaloid isolated from the plant Piper nigrum. It has a role as a NF-kappaB inhibitor, a plant metabolite, a food component and a human blood serum metabolite.

Furthermore, piperine has also been documented for its hepatoprotective, anti-allergic, anti-inflammatory, and neuroprotective properties. This review highlights and discusses the medicinal and health-promoting effects of piperine, along with possible mechanisms of its action in health promotion and disease prevention.

Piperine’s toxicity affects mainly the reproductive system . Piperine (10 mg/kg, p.o.) induced an increase in serum gonadotropins and a decrease in intratesticular testosterone in male albino rats; reports were also there that piperine interferes with crucial reproductive events in a Swiss albino-mammalian model .

Piperine is a plant-derived promising piperamide candidate isolated from the black pepper (Piper nigrum L.). In the last few years, this natural botanical product and its derivatives have aroused much attention for their comprehensive biological activities, including not only medical but also agricultural bioactivities.