Dyskeratosis congenita (DKC) is a rare human genetic disorder affecting telomere replication. Mutations in the genes encoding the protein or RNA subunits of telomerase result in very short telomeres. DKC symptoms include bone marrow failure (reduced production of blood cells) and anemia. If symptoms are

Scenario 1: Dyskeratosis congenita (DKC) is a rare human genetic disorder affecting telomere replication. Mutations in the genes encoding telomerase enzymes result in telomeres with RNA subunits that do not read 3'-CAACCCCAAC-5'. DKC symptoms include bone marrow failure (reduced production of blood cells) and anemia.

Dyskeratosis Congenita (DC): Dyskeratosis Congenita is an infrequent inherited bone marrow failure syndrome described by mucocutaneous abnormalities as nail dystrophy, hyperpigmentation, and leukoplakia. is an acute form of DC in BMF disease characterized by immunodeficiency, microcephaly, cerebellar hypoplasia, intrauterine increase ...

Dyskeratosis congenita is an inherited human disorder in which patients have reduced telomerase activity. Affected individuals die between the ages of 16 and 50 years. Death is usually associated with bone marrow failure, although the patient will exhibit many other symptoms.

35. Dyskeratosis congenita (DKC) is a rare genetic disorder characterized by abnormal fingernails and skin pigmentation, the formation of white patches on the tongue and cheek, and progressive failure of the bone marrow. An autosomal dominant form of DKC results from mutations in the gene that encodes the RNA component of telomerase.

Dyskeratosis congenita (DKC) is a rare human genetic disorderaffecting telomere replication. Mutations in thegenes encoding the protein or RNA subunits of telomeraseresult in very short telomeres. DKC symptoms include bonemarrow failure (reduced production of blood cells) and anemia.If symptoms are severe, a bone marrow transplant may be ...

Dyskeratosis congenita (DKC) is a rare genetic disorder characterized by abnormal fingernails and skin pigmentation, the formation of white patches on the tongue and cheek, and progressive failure of the bone marrow. An autosomal dominant form of DKC results from mutations in the gene that encodes the RNA component of telomerase.

Dyskeratosis congenita is an inherited human disorder in which patients have reduced telomerase activity. Affected individuals die between the ages of 16 and 50 years. Death is usually associated with bone marrow failure, although the patient will exhibit many other symptoms.