In molecular biology, a protein domain is a region of a protein's polypeptide chain that is self-stabilizing and that folds independently from the rest. Each domain forms a compact folded three-dimensional structure. Many proteins consist of several domains, and a domain may appear in a variety of different proteins.

蛋白质结构域（英語： protein domain ）是蛋白质 多肽链中具有特异结构和独立功能的区域，能自稳定，独立于其他区域折叠，其构成蛋白质三级结构的基本单元。

InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.

Domain names often derive from their prominent biological function in the protein they belong to (e.g., the calcium-binding domain of calmodulin), or from their discoverers (the PH domain!). The domain swapping that gives rise to gene families and superfamilies are natural genetic events.

2018年8月11日 · Protein domains：是一种结构实体，通常代表蛋白质结构中独立折叠和行驶功能的一部分。因此，蛋白质经常是这些结构域的不同的组合构建起来的。 那，motif和domains之间有什么联系？当你考虑蛋白质家族的时候，不仅要看整个序列，还有关注单独结构域。

结构域（domain）是位于超二级结构和三级结构间的一个层次。 结构域是在蛋白质的三级结构内的独立折叠单元，通常都是几个超二级结构单元的组合。 在较大的蛋白质分子中，由于多肽链上相邻的超二级结构紧密联系，进一步折叠形成一个或多个相对独立的 ...

Domains are distinct functional and/or structural units in a protein. Usually they are responsible for a particular function or interaction, contributing to the overall role of a protein. Domains may exist in a variety of biological contexts, where similar domains can be …

These resources cover databases and tools to help in the study of macromolecular structures, conserved domains and protein classification, small molecules and their biological activity, and biological pathways and systems.

Protein domains are the basic units of proteins that can fold, function, and evolve independently. Knowledge of protein domains is critical for protein classification, understanding their biological functions, annotating their evolutionary ...

Conserved domains are functional units within a protein that act as building blocks in molecular evolution and recombine in various arrangements to make proteins with different functions.