2024年11月26日 · Trimebutine relieves abdominal pain and helps to restore normal bowel function and may be used to treat motility disorders of the gastrointestinal tract such as irritable bowel syndrome and paralytic ileus after abdominal surgery.

Trimebutine is a drug with antimuscarinic and very weak mu opioid agonist effects. [1] It is used for the treatment of irritable bowel syndrome and other gastrointestinal disorders. The major product from drug metabolism of trimebutine in human beings is nortrimebutine, [2] which comes from removal of one of the methyl groups attached to the ...

是一种胃肠解痉药，对胃肠道平滑肌具有较强的松弛作用，能缓解各种原因引起的痉挛。 1.用于慢性胃炎引起的胃肠道症状 (如腹部胀满感、腹部疼痛、嗳气等)。 2.用于 肠易激综合征。 3.用于术后肠道功能的恢复。 4.用于钡剂灌肠检查，可加速钡剂灌肠检查的进程。 1.孕妇、哺乳期妇女。 2.儿童。 3.对曲美布汀过敏者。 1.用于慢性胃炎引起的胃肠道症状 (如腹部胀满感、腹部疼痛、嗳气等)。 2.用于 肠易激综合征。 3.用于术后肠道功能的恢复。 4.用于钡剂灌肠检查，可加速钡剂灌 …

Trimebutine is a spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery.

Trimebutine belongs to the class of medications called spasmolytics. It is used to treat irritable bowel syndrome (spastic colon). This condition is caused by overactive movements of the bowels. Trimebutine works by slowing down or normalizing the abnormal movements of the bowel.

USES: This medication helps regulate movement of the intestinal tract. It is used to treat symptoms of irritable bowel syndrome (spastic colon). It may also be used after intestinal surgery. HOW TO USE: Take this by mouth as directed before meals usually three times a day.

This article provides an overview of the current knowledge on the pharmacological mechanisms of trimebutine and its clinical applications in gastrointestinal disorders. Its biochemical properties and the complex mechanisms of action, along with a well-studied pharmacological safety, make this compound still actual and valuable.

Trimebutine accelerates gastric emptying, induces premature phase III of the migrating motor complex in the intestine and modulates the contractile activity of the colon. Recently, trimebutine has also been shown to decrease reflexes induced by distension of the gut lumen in animals and it may therefore modulate visceral sensitivity.

马来酸曲美布汀，是一种 有机化合物，化学式为C26H33NO9，主要用作 解痉药，用于胃肠道运动 功能紊乱 引起的 食欲不振 、恶心、呕吐、 嗳气 、 腹胀 、 腹鸣 、 腹痛 、腹泻便秘等症状的改善以及肠道易激惹综合征。 本品为 (±)- 3,4,5-三甲氧基苯甲酸 (2- 二甲氨基 -2- 苯基) 丁酯 马来酸 盐，按干燥品计算，含C22H29NO5·C4H4O4不得少于99.0%。 本品为白色结晶或 结晶性 粉末，无臭。 本品在 甲醇 或 乙腈 中溶解，在水或 无水乙醇 中微溶，在 乙醚 中几乎不溶，在 冰醋酸 …

Trimebutine maleate的藥理作用 阻斷鈣離子進入細胞，達到抑制平滑肌收縮的效果，作為解痙藥，治療腸躁症、術後麻痺性腸阻塞之腹痛與腹部不適。 阻斷鈣離子進入細胞，達到抑制平滑肌收縮的效果，因此可緩解胃部不適的症狀。