γ-Butyrolactone (GBL) or gamma-butyrolactone is an organic compound with the formula O=CO(CH 2) 3. It is a hygroscopic, colorless, water-miscible liquid with a weak characteristic odor. It is the simplest 4-carbon lactone. It is mainly used as an intermediate in the production of other chemicals, such as N-methyl-2-pyrrolidone. [5]

gamma-Butyrolactone | C4H6O2 | CID 7302 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

This update will help to develop biologically active new γ-butyrolactones and to solve hurdles in the synthesis of γ-butyrolactone-bearing natural products and pharmaceuticals as well as to develop novel synthetic approaches toward γ-butyrolactones.

γ-Butyrolactone (GBL) hormones regulate antibiotic production in many Streptomyces species. GBL-based systems could be used to design orthogonal switches in synthetic biology. The GBL receptor ScbR has been used in mammalian synthetic switches.

2007年9月11日 · gamma-Butyrolactone DrugBank Accession Number DB04699 Background. One of the furans with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent. Type Small Molecule Groups Experimental, Illicit ...

gamma-butyrolactone (GBL) and 1,4-butanediol are GHB precursors and have similar actions. Early features of toxicity include headache, agitation, ataxia, hypersalivation and gastrointestinal disturbances, progressing to confusion and agitation with drowsiness, urinary incontinence, tremor and myoclonus.

General Information About gamma-Butyrolactone (GBL) gamma-Butyrolactone, commonly known as GBL, is a lactone and the simplest 4-carbon cyclic ester. Structurally, its molecule consists of an oxygen atom bonded to a carbonyl group (C=O), while the other three carbons and an oxygen create the ringed cyclic formation.