2003年7月18日 · 1Q11 Crystal structure of an active fragment of human tyrosyl-tRNA synthetase with tyrosinol. PDB DOI: https://doi.org/10.2210/pdb1Q11/pdb; Classification: LIGASE; Organism(s): Homo sapiens; Expression System: Escherichia coli; Mutation(s): No ; Deposited: 2003-07-18 Released: 2004-01-06 ; Deposition Author(s): Yang, X.-L., Schimmel, P., Ribas ...

Biological Unit for 1Q11: dimeric; determined by author and by software (PISA,PQS)

We report a case of inherited proximal duplication of chromosome 1q in an 11 year old boy presenting with T lymphoblastic lymphoma/leukaemia. The duplication of chromosome 1 (q11q22) was identified using G banding and confirmed with comparative genomic hybridisation.

The breakpoints in 1q varied from 1q11 to 1q43, with a clustering to 1q21-23, and the 5q breaks occurred in 5q11 to 5q35, mainly in the distal 5q3 region.

2004年1月6日 · 1q11: Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains.

1q11 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. …

1Q11: Crystal structure of an active fragment of human tyrosyl-tRNA synthetase with tyrosinol

Unbalanced whole-arm translocations (WATs) of the long arm of chromosome 1, resulting in complete trisomy 1q, are chromosomal abnormalities detectable in both solid tumors and hematologic neoplasms.

2000年4月1日 · Fluorescence in situ hybridization (FISH) confirmed the identification of 11q material in the derivative chromosomes. While 1q has been the most common donor of acquired jumping translocations, this is the first report on jumping translocations of 11q.

PDB Entry - 1Q11 (Status - Released) Summary information: Title: Crystal structure of an active fragment of human tyrosyl-tRNA synthetase with tyrosinol. PDB DOI: https://doi.org/10.2210/pdb1q11/pdb. Primary publication DOI: https://doi.org/10.1073/pnas.2136794100. Entry authors: Yang, X.-L., Schimmel, P., Ribas de …