Alvimopan is a competitive antagonist of the μ-opioid receptors (MOR) in the gastrointestinal tract, with a Ki of 0.2 ng/mL. Activation of these receptors by endogenous or exogenous agonists …

What is alvimopan? Alvimopan reduces certain side effects of opioid medicine used to prevent pain after surgery. Some side effects of opioid medicine (stomach pain, bloating, constipation) …

2024年4月30日 · Entereg (alvimopan) is used to speed recovery of stomach and intestinal functions after a gastrointestinal surgery. Includes Entereg side effects, interactions and …

Alvimopan is used to help the bowel recover more quickly after bowel surgery, so that you can eat solid foods and have regular bowel movements. Alvimopan is in a class of medications called …

2011年4月15日 · Alvimopan (Entereg) is an oral, peripherally-acting mu-opioid receptor antagonist used to accelerate the time to upper and lower gastrointestinal recovery following …

2024年7月1日 · Alvimopan is used to help restore normal bowel function in patients who have just had bowel resection surgery. This medicine works by blocking the effects of certain …

2023年11月5日 · Alvimopan (Entereg) is an opioid antagonist. It helps adults recover more quickly from intestinal (gut) surgery by reversing the effects of opioid pain medication on the bowels. …

2008年3月19日 · Alvimopan is an opioid antagonist used to reduce healing time of the upper and lower gastrointestinal tract following surgical procedures that involve bowel resection with …

2018年4月21日 · ENTEREG Capsules contain alvimopan, a peripherally-acting µ-opioid receptor (PAM-OR) antagonist. Chemically, alvimopan is the single stereoisomer [ [2 (S)- [ [4 (R)- (3 …

An opioid receptor antagonist which blocks opioid binding at the mu receptor; alvimopan has restricted ability to cross the blood-brain barrier at therapeutic doses. It selectively and …