Activator protein 1 (AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and bacterial and viral infections. [1]

The AP-1 transcription factor is a dimeric transcription factor composed of proteins from several families including Jun, Fos, ATF, and Maf. It regulates various cell-autonomous as well as general physiological and pathological effects, and is involved in processes such as proliferation, differentiation, apoptosis, migration and wound healing ...

The dimeric transcription factor complex Activator Protein-1 (AP-1) is a group of proteins involved in a wide array of cell processes and a critical regulator of nuclear gene expression during T-cell activation.

Activator protein-1 (AP-1) is an inducible transcription factor that consists of a diverse group of members including Jun, Fos, Maf, and ATF. AP-1 involves a number of processes such as proliferation, migration, and survival in cells.

2017年4月15日 · Protein target information for Transcription factor AP-1 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

AP-1 (activating protein-1) is a collective term referring to dimeric transcription factors composed of Jun, Fos or ATF (activating transcription factor) subunits that bind to a common DNA site, the AP-1-binding site.

2002年5月1日 · AP-1 was one of the first mammalian transcription factors to be identified 1, but its physiological functions are still being unravelled. AP-1 activity is induced by a plethora of...

Transcription factors (TFs) play a crucial role in the maintenance of cellular homeostasis by binding to DNA regulatory sequences thereby modulating the rate of gene transcription. Activator Protein-1 (AP-1) was one of the first mammalian TFs to be identified [1].

The AP-1 is a transcription factor belonging to the c-Fos, c-Jun, activating transcription factor (ATF) and Jun dimerization protein (JDP) families and controls a number of cellular processes including differentiation, proliferation, and apoptosis.

Activator protein 1 (AP-1) is another family of bZIP transcription factors that play a central role in the regulation of neural gene expression by extracellular signals. The AP-1 family comprises multiple proteins that bind as heterodimers (and a few as …