Mitochondrial segmentation and function prediction in live-cell images ...
2025年1月16日 · The cell lines L02 (human normal liver cell, CL-0111) and A2780 (human ovarian cancer cells, CL-0013) were purchased from Procell Life Science & Technology Co., Ltd. Cells were cultured under ...
Nanocarrier imaging at single-cell resolution across entire ... - Nature
2025年1月14日 · a–f, Cell-level resolution biodistribution of non-targeted and CX3CR1 antibody immune-cell-targeted (illustrated on the left) origami throughout the entire mouse body (c,d) and in detailed views ...
Label-free nanoscopy of cell metabolism by ultrasensitive ... - Nature
2025年1月16日 · Figure 4b presents an image at a depth of 19.3 µm, along with a maximum projection and a color-coded axial projection, providing the 3D morphology of nanoscopic structures within ZIKV-infected cells.
Applied to image data, these algorithms can derive a more robust and consistent definition of the features that represent cells and other biological objects — not just in a given set of...
Cell Painting: a decade of discovery and innovation in ... - Nature
2024年12月5日 · Here, we review a decade of advancements and applications of Cell Painting, a microscopy-based cell-labeling assay aiming to capture a cell’s state, introduced in 2013 to optimize and...
Mitotic chromatin marking governs the segregation of DNA ... - Nature
2025年1月16日 · a Left: Experimental procedure for synchronizing cells, inflicting UV irradiation in late G2, and imaging UV damage segregation in G1 cells. Immunofluorescence images show an example of G1 ...
Deep Learning in Cell Image Analysis - Intelligent Computing
2022年9月7日 · Cell images, which have been widely used in biomedical research and drug discovery, contain a great deal of valuable information that encodes how cells respond to external stimuli and intentional perturbations. Meanwhile, to discover rarer phenotypes, cell imaging is frequently performed in a high-content manner.
Multiplexed high-throughput immune cell imaging reveals
2022年11月2日 · To be able to comprehensively measure immune cell phenotypes, we developed a multiplexed immunofluorescence approach for PBMCs that extends our previously developed protocol for high-throughput image-based screening in human biopsies compatible with mixed nonadherent cells (40–42).
Long-term, real-time and label-free live cell image processing and ...
2023年10月1日 · In this study, we combined a deep learning algorithm with the watershed segmentation method to segment approximately 21,600,000 label-free BGC-823 and MGC-803 cells in about 55,000 images. We explored cell proliferative ability, morphological characteristics, and movement ability under drug treatment.
Deep imaging of LepR+ stromal cells in optically cleared ... - Nature
2025年1月13日 · Hematopoietic stem/progenitor cells locate near the vessels in adult bone marrow. a 2D projected images of thick specimen. Lineage − c-kit + hematopoietic stem/progenitor cells are in close ...