Central chemoreceptors, first localized to areas on the ventral surface of the medulla, now are thought to be present in many locations within the brainstem, cerebellum, hypothalamus and midbrain (133, 143, 144, 158, 166, 226, 257).

2022年5月19日 · Central chemoreceptors are located in the medulla oblongata of the brainstem. They detect changes in the arterial partial pressure of carbon dioxide (pCO 2). When changes are detected, the receptors send impulses to the respiratory centres in the brainstem that initiate changes in ventilation to restore normal pCO 2.

Central chemoreceptors are sensors located within the brain that are responsible for detecting changes in CO2 levels and/or pH. These chemoreceptors have a widespread distribution and play a vital role in maintaining normal breathing patterns and activity among neurons involved in respiratory control.

central chemoreceptors: Located within the medulla, they are sensitive to the pH of their environment. peripheral chemoreceptors: The aoritic and carotid bodies, which act principally to detect variation of the oxygen concentration in the arterial blood, also monitor arterial carbon dioxide and pH.

Central chemoreception responds to small variations in PCO2 to regulate normal gas exchange and to large changes in PCO2 to minimize acid-base changes. Central chemoreceptor sites vary in function with sex and with development.

2024年12月11日 · The central chemoreceptors are primarily located on the ventral medulla and especially in the retrotrapezoid nucleus. They monitor the acidity (pH) of the cerebrospinal fluid, which is a good indicator of blood carbon dioxide levels.

2024年10月10日 · The central chemoreceptors play a role in long-term regulation of breathing and are essential for maintaining homeostatic balance during metabolic changes. Their response to hypercapnia—elevated levels of carbon dioxide—is a key aspect of the body’s strategy to maintain stable internal conditions.

The central chemoreceptors are the primary sensors for the ventilatory response to changes in Pa CO 2. The main central chemoreceptors are located on the surface of the ventral medulla, but there are others elsewhere in the brain, especially close to the retrotrapezoid nucleus.

Owing to these unresolved issues, the concept of central respiratory chemoreceptors remains a work in progress. In this context, we believe a better term to use should be CO 2 sensors instead of CO 2 chemoreceptors. This is because CO 2 sensors are not only receptors located in neurons, but also different sensors that can be in glial cells ...

2012年1月1日 · Central chemoreception responds to small variations in PCO 2 to regulate normal gas exchange and to large changes in PCO 2 to minimize acid-base changes. Central chemoreceptor sites vary in function with sex and with development.