Fibrin ring granuloma - Wikipedia
A fibrin ring granuloma, also known as doughnut granuloma, is a histopathological finding that is characteristic of Q fever. [1] On hematoxylin-eosin staining , the fibrin ring granuloma consists of a central lipid vacuole (usually washed-out during fixing and staining, leaving only an empty hole) surrounded by a dense red fibrin ring and ...
Fibrin Ring Granuloma - an overview | ScienceDirect Topics
Fibrin-ring granulomas are an unusual variant characterized by the presence of an epithelioid granuloma with a central lipid vacuole and a surrounding ring of fibrin.
Pathology Outlines - Granulomatous hepatitis
2023年5月30日 · Fibrin ring granuloma (also known as doughnut granuloma; central fat globule surrounded by a circumferential rim of fibrin and histiocytes) is originally pathognomonic for Q fever (Coxiella burnetii) but now considered as nonspecific features.
Pathology Outlines - Granulomatous inflammation
2022年8月5日 · Ring or doughnut granuloma: fibrin and inflammatory cells arranged around a central clear space; associated with Q fever but not specific, can also be seen in Brucella, typhoid, rare viral infections
Granulomatous liver diseases - PMC
Fibrin-ring granulomas were initially described in association with granulomatous hepatitis in Coxiella burnetii infection (Q fever) by Bernstein. 40 Their distinct feature is the presence of a central round fat vacuole surrounded by a fibrin ring and an outer layer of histiocytes. They are usually small in size and intralobular.
Bone Marrow Granulomatosis in Acute Q Fever - PMC - National …
2021年10月14日 · We report a case of acute Q fever with hepatic and bone marrow involvement presented as fever of unknown origin (FUO) in a 56-year-old sportive hunter man. Typical fibrin ring granulomas (doughnut granulomas) were found in the bone marrow biopsy and were essential for the diagnosis.
Fibrin Ring Granulomas in Checkpoint Inhibitor-induced Hepatitis
Fibrin ring granulomas are an uncommon finding in liver biopsies although they have been described in liver injury secondary to several infectious and noninfectious entities, most notably Q fever.
Hepatic fibrin-ring granulomas: A clinicopathologic study of 23 ...
1991年6月1日 · This report broadens the range of etiologies of hepatic fibrin-ring granulomas to include boutonneuse fever and toxoplasmosis in the differential diagnosis of firing granulomas, and it could serve as a guideline to the clinician and pathologist for the most frequent categories of disease associated with this morphologic pattern.
Ring around the Diagnosis | New England Journal of Medicine
2006年5月4日 · Fibrin-ring granulomas are usually associated with Q fever, but they may also occur with CMV, EBV, and mycobacterial infections; lymphoma; vasculitis; and typhoid fever.
[Bone marrow fibrin-ring granuloma: review of 24 cases]
Background: Fibrin-ring granuloma (FRG), which can be found in bone marrow or the liver, is a subtype of epithelioid granuloma characterized by a central fat vacuole and annular peripheral fibrinoid materials.
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