A histiocyte is a vertebrate cell that is part of the mononuclear phagocyte system (also known as the reticuloendothelial system or lymphoreticular system). The mononuclear phagocytic system is part of the organism's immune system.

2023年8月1日 · Histiocytosis is a rare group of conditions that occur when your body makes abnormal (mutant) white blood cells called histiocytes. Normal histiocytes help tune up your body’s defenses against multiple pathogens (like viruses, bacteria, fungi and parasites).

Histiocytes are a type of immune cell that are part of the body’s defense mechanism against infections and foreign substances. They belong to the mononuclear phagocyte system including monocytes in the blood and macrophages in tissues. Histiocytes play an important role in the immune system’s response to pathogens and tissue repair and maintenance.

Histiocytosis is a generic name for a group of syndromes characterized by an abnormal increase in the number of certain immune cells called histiocytes. These include monocytes, macrophages, and dendritic cells.

Histiocytoses are a group of diseases characterised by the proliferation of macrophages and dendritic cells in different tissues, resulting in tissue damage. 1,2. There are about 100 subtypes of histiocytosis.

The Histiocytosis Association is a global nonprofit organization dedicated to addressing the unique needs of patients and families dealing with the effects of histiocytic disorders while leading the search for a cure. $7.5 million in total research funded that is resulting in fewer patient fatalities and more effective treatments.

2016年9月26日 · Adult histiocyte disorders are a group of rare diseases that involve an over-production of white blood cells known as histiocytes, which destroy foreign substances and protect the body from infection. In adults, Langerhans cell histiocytosis (LCH) is the most common of these diseases.

2021年3月1日 · Histiocytes are differentiated cells of the mononuclear phagocyte system, i.e. a part of the immune system comprised of the phagocytic cells found in reticular connective tissue.

1994年11月1日 · The term histiocyte refers to cells of either the macrophage or Langerhans cell lineages. The histiocytic disorders are characterized by the proliferation of cells of these lineages.

The term histiocyte refers to a bone marrow–derived progenitor cell that differentiates, depending on the cytokine and growth factor milieu, into a dendritic antigen presenting cell (Langerhans cell, dermal dendrocyte) or a phagocytic cell (tissue macrophage).