Lowering the intrathecal pressure (ITP) by draining CSF is routinely done in thoracoabdominal aortic aneurysm surgery but has not been evaluated in the setting of acute traumatic SCI.

2017年9月15日 · To determine whether spinal cord perfusion pressure (SCPP) as measured with a lumbar intrathecal catheter is a more predictive measure of neurologic outcome than the conventionally measured mean arterial pressure (MAP).

2024年1月1日 · Another way of measuring pressure is by inserting a lumbar catheter (Squair et al., 2017; Kwon et al., 2009). This pressure, termed intrathecal pressure (ITP), is the CSFP in the lumbar subarachnoid space.

Elevated ISP is a time-dependent process that is mainly caused by hemorrhage, edema, and blood-spinal cord barrier destruction and peaks at 3 days after traumatic spinal cord injury. Duraplasty and hypertonic saline may be promising treatments for …

Intracranial pressure is not constant and on a long-term scale (hours), depends on the balance of CSF production and drainage. On a shorter-term scale (seconds), ICP fluctuates due to the rhythmic changes of the cerebral blood volume (and respiratory fluctuations).

2024年10月16日 · Current research aims to develop individualised management based on ISP/ITP and SCPP monitoring. These techniques are experimental. A key controversy is whether the spinal cord pressure is best measured from the injury site (ISP) or from the lumbar cerebrospinal fluid (ITP).

Increases in intracranial pressure (ICP) following traumatic brain injury (TBI) have long been considered a keystone for clinical management.