2009年8月5日 · If you take Lipitor, you should not drink or take any substance which includes grapefruit. Grapefruit can interact with lipitor (a cholesterol-lowering statin) causing an increase in the level of the medication in your blood. Clinical studies have shown a significant increase in the level of lipitor when consuming grapefruit.

2018年1月25日 · Per the Lipitor package insert, one study showed that drinking one glass of grapefruit juice (8 ounces) with atorvastatin resulted in an increased drug concentration of 37%. Drinking excessive amounts of grapefruit (approximately 1 L/day) increased drug …

2023年10月12日 · Avoid consuming grapefruit products and drinking more than 1.2 liters of grapefruit juice each day. Lipitor side effects Get emergency medical help if you have signs of an allergic reaction to Lipitor (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat , burning eyes, skin pain, red or ...

2019年6月17日 · Nevertheless, other studies theorize that only large amounts of grapefruit consumption would cause a clinically significant interaction, and this may be the case with Lipitor specifically. The FDA-approved prescribing information for Lipitor does warn about a grapefruit juice interaction, but only when consuming very large amounts (1.2 liters ...

2017年9月28日 · Grapefruit interacts with many different medications in many different ways. The most notable mechanism is by the inhibition of an enzyme known as CYP3A enzyme. This enzyme is extremely important in the breakdown of many compounds, including drugs like Lipitor and simvastatin.

2024年4月16日 · Lipitor belongs to the class of medicines known as statins. Lipitor is also known as an HMG-CoA reductase inhibitor. 2. Upsides. Lipitor, in conjunction with dietary measures, may be used for the treatment of high cholesterol in people at increased risk of cardiovascular disease if initial dietary measures fail to lower cholesterol.

2010年5月6日 · Grapefruit juice blocks special enzymes in the wall of the small intestine that actually destroy many medications, including Lipitor, and prevents their absorption into the body. Thus, in the normal state, smaller amounts of the drugs get into the body than are ingested.

Atorvastatin calcium (brand name: Lipitor) is a medicine in a class of drugs called HMG CoA reductase inhibitors, also referred to as "statins." Pfizer’s Lipitor was first approved in 1996 and is considered one of the most successful selling drugs of all time. In 2006, Lipitor had the top U.S. drug sales of over $13 billion.

Grapefruit juice can increase the blood levels of atorvastatin. This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue.

Grapefruit juice can increase the blood levels of atorvastatin. This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. In some cases, rhabdomyolysis can cause kidney damage and even death.