Lissencephaly (/ ˌlɪs.ɛnˈsɛf.əl.i /, meaning 'smooth brain') [1] is a set of rare brain disorders whereby the whole or parts of the surface of the brain appear smooth. [2] . It is caused by defective neuronal migration during the 12th to 24th weeks of gestation, resulting in a lack of development of brain folds (gyri) and grooves (sulci). [3] .

La lisencefalia(que significa "cerebro liso") es una malformación cerebral rara en que no hay convoluciones (pliegues) normales en la corteza cerebral y en que la cabeza es más pequeña que lo normal (microcefalia).[1] .

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2023年5月4日 · Lissencephaly is a rare condition that causes a child’s brain to develop the wrong way during pregnancy. A child with the disorder may have an unusual-looking face or...

2025年1月3日 · It is a basket term for a number of congenital cortical malformations characterized by absent or minimal sulcation. Lissencephaly-pachygyria can be further divided into types I (classic) and type II (cobblestone).

2024年11月29日 · Lissencephaly type I, also known as classic lissencephaly, is a heterogeneous group of disorders of cortical formation characterized by a smooth brain with absent or hypoplastic sulci.

Lissencephaly (LIS) is a spectrum that includes various brain malformations. [1] . Its prevalence is estimated at 11.7 to 40 per million births. [2] The prognosis depends on the severity of the syndrome. Most children remain in an early developmental level and have a short life expectancy, many dying before 10 years old.

2024年6月30日 · Lissencephaly is a malformation of cortical development, where there is deficient gyration (folding) in the cerebral cortex, resulting in absent gyri (agyria) and/or broad simple gyri (pachygyria). There are two major types of lissencephaly:

2023年1月24日 · Lissencephaly is an uncommon neurological condition that often results in severe developmental delays and difficult to control seizures. It is a condition that results from the defective migration of nerve cells during fetal development. The word lissencephaly comes from two Greek words: lissos, meaning "smooth," and enkaphalos, meaning "brain."

Antecedentes: El espectro de lisencefalia (LIS) corresponde a un grupo de graves malformaciones cerebrales en la corte-za causadas por un fallo en la migración neuronal. El espectro incluye agiria, paquigiria y heterotopía de banda subcortical (SBH).