2003年5月1日 · The article by Meyer et al. revives a debate regarding the appropriateness of metformin use for people with type 1 diabetes. Given the potential for coexisting lactic acidosis and diabetic ketoacidosis, how can one justify its use?

2024年4月30日 · Metformin can help reduce insulin resistance and aid in weight management for people with type 1 diabetes, but it also carries potential side effects like gastrointestinal discomfort.

Metformin improved diabetic control with reduced insulin dose requirement without weight loss in overweight adults with C-peptide-negative type 1 diabetes during 4 months’ therapy . Metformin improved poor glycemic control as well as insulin resistance in adolescents with type 1 diabetes who were on high-dose insulin therapy [17, 18].

2022年9月29日 · The benefits of metformin absolutely make sense in supporting a person with type 1 diabetes—and it’s a very affordable medication. Talk to your health care team if you think taking metformin might help you with your diabetes management goals!

Recently-published findings from the REducing with MetfOrmin Vascular Adverse Lesions (REMOVAL) trial suggest that metformin therapy in type 1 diabetes can reduce atherosclerosis progression, weight and LDL-cholesterol levels.

2024年5月13日 · You may already know that metformin is a popular medication for people with type 2 diabetes. What you might not be aware of is that a number of people with type 1 diabetes also take metformin to help with issues like insulin resistance, excess weight, and …

Metformin reduces insulin-dose requirement in type 1 diabetes but it is unclear whether this is sustained beyond 1 year and whether there are benefits for cardiovascular and other key clinical outcomes.

Aims/hypothesis As adding metformin to insulin therapy has been advocated in type 1 diabetes, we conducted a systematic review of published clinical trials and clinical trial databases to assess the effects on HbA1c, weight, insulin-dose requirement and adverse effects.

2018年1月16日 · The addition of metformin in type 1 diabetes improves insulin sensitivity, diabetic control, body composition and patient well-being. Diabetes Obes Metab. 2007;9:143–5.

Studies have shown that metformin may benefit those insulin-resistant individuals with T1DM. This meta-analysis was performed to provide the evidence of clinical efficacy and safety of metformin in T1DM.