Molecular imprinting is a technique to create template-shaped cavities in polymer matrices with predetermined selectivity and high affinity. [1] This technique is based on the system used by enzymes for substrate recognition, which is called the "lock and key" model.

2016年3月3日 · Molecular imprinting technology (MIT), often described as a method of making a molecular lock to match a molecular key, is a technique for the creation of molecularly imprinted polymers (MIPs) with tailor-made binding sites complementary to the template molecules in shape, size and functional groups.

Molecular imprinting is a process in which selected functional monomers are allowed to self-assemble around a template molecule and are subsequently polymerized in the presence of a crosslinker.

2021年12月1日 · Molecular imprinting technology (MIT), proposed by Polyakov in 1930, is an emerging and exploring technique which involves the fabrication of artificial receptor sorbents of target molecule on a polymer network.

Molecular imprinting represents the most generic, versatile, scalable, and cost-effective approach to the creation of synthetic molecular receptors for small molecules and cells to date. The approaches reported so far range from whole-cell imprinting to targeting specific and distinctive cell-surface components.

There are a variety of molecular imprinting techniques used for the preparation of biomimetic sensors including bulk imprinting, surface imprinting (soft lithography, template immobilization, grafting, emulsion polymerization) and epitope imprinting.

2021年8月23日 · In contrast, molecular imprinting is a method of constructing a molecule, with specific recognition properties, by having the ligand itself direct the assembly of the desired structure. The general approach of the technique is to combine the desired "imprint" molecule with a solution of small monomeric molecules which has several desired features.

Molecular imprinting is a general strategy of synthesis that allows tailor-made polymeric materials to be obtained with memory. The concept of molecular imprinting emerged in 1940 following Linus Pauling's theory about the formation of antibodies.

2016年4月21日 · Molecular imprinting technology (MIT), often described as a method of making a molecular lock to match a molecular key, is a technique for the creation of molecularly imprinted polymers (MIPs) with tailor-made binding sites complementary to the template molecules in shape, size and functional groups.

2019年5月21日 · In this review, the characteristics, morphologies, and applicability of currently popular carrier materials for molecular imprinting, especially the fundamental role of hydrogels, porous materials, hierarchical nanoparticles, and 2D materials in the separation and recognition of biological templates are discussed.