Synaptic plasticity rule for gradient estimation by dynamic perturbation of conductances. In neuroscience, synaptic plasticity is the ability of synapses to strengthen or weaken over time, in response to increases or decreases in their activity. [1]

Synaptic plasticity is change that occurs at synapses, the junctions between neurons that allow them to communicate. The idea that synapses could change, and that this change depended on how active or inactive they were, was first proposed …

2007年8月29日 · Here, we review current understanding of the mechanisms of the major forms of synaptic plasticity at excitatory synapses in the mammalian brain.

Studies of brain network connectivity improved understanding on brain changes and adaptation in response to different pathologies. Synaptic plasticity, the ability of neurons to modify their connections, is involved in brain network remodeling following different types of brain damage (e.g., vascular, neurodegenerative, inflammatory).

2020年7月8日 · Synaptic plasticity, the activity-dependent change in neuronal connection strength, has long been considered an important component of learning and memory. Computational and engineering work corroborate the power of learning through the directed adjustment of connection weights.

synaptic plasticity in any number of different brain regions is critical for understanding the neural basis of many aspects of normal and pathological brain function.

This process of experience-dependent changes in synaptic connectivity is called synaptic plasticity. Studies of synaptic plasticity have begun to detail the molecular mechanisms that underlie these synaptic changes.

Synaptic plasticity (changes in synaptic strength) is a fundamental property of neurons that occurs virtually at every synapse in the brain. Synaptic plasticity serves as an experience-dependent mechanism for the adaptability of behavior and memory processes.

2023年7月27日 · In this article, we will explore the core principles and types of synaptic plasticity. We will have a closer look at long term potentiation (LTP) and long term depression (LTD) and their molecular mechanisms.

Here, we review current understanding of the mechanisms of the major forms of synaptic plasticity at excitatory synapses in the mammalian brain. We also provide examples of the possible developmental and behavioral functions of synaptic plasticity and how maladaptive synaptic plasticity may contribute to neuropsychiatric disorders.