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- Topoisomerase IV is an enzyme in bacteria that helps to separate replicated DNA strands during cell division.了解详细信息：Topoisomerase IV is an enzyme in bacteria that helps to separate replicated DNA strands during cell division.library.fiveable.me/key-terms/microbio/topoisomera…Topoisomerase IV (TopoIV) is a vital bacterial enzyme which disentangles newly replicated DNA and enables segregation of daughter chromosomes.www.nature.com/articles/s41598-020-80043-4Topoisomerase IV (Topo IV), an essential ATP-dependent bacterial type II topoisomerase, transports one segment of DNA through a transient double-strand break in a second segment of DNA.www.pnas.org/doi/10.1073/pnas.0900574106
DNA gyrase, topoisomerase IV, and the 4-quinolones - PubMed
The key event in quinolone action is reversible trapping of gyrase-DNA and topoisomerase IV-DNA complexes. Complex formation with gyrase is followed by a rapid, reversible inhibition of …
- 作者: Karl Drlica, Xilin Zhao
- Publish Year: 1997
Topoisomerase IV - an overview | ScienceDirect Topics
Topoisomerase IV is an A 2 B 2 tetramer that is comprised of two distinct subunits, ParC (molecular mass ≈88 kDa), and ParE (molecular mass ≈70 kDa), which are homologous to the …
DNA gyrase and topoisomerase IV: biochemical activities, …
1998年10月1日 · DNA gyrase and topoisomerase IV are the two type II topoisomerases present in bacteria. Though clearly related, based on amino acid sequence similarity, they each play …
- 作者: Cindy Levine, Hiroshi Hiasa, Kenneth J. Marians, Kenneth J. Marians
- Publish Year: 1998
DNA gyrase, topoisomerase IV, and the 4-quinolones. - PubMed …
It is now clear that topoisomerase IV, rather than gyrase, is responsible for decatenation of interlinked chromosomes. Moreover, topoisomerase IV is a target of the 4-quinolones, …
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Topoisomerase IV tracks behind the replication fork and the SeqA ...
2021年1月12日 · Topoisomerase IV (TopoIV) is a vital bacterial enzyme which disentangles newly replicated DNA and enables segregation of daughter chromosomes. In bacteria, DNA …
Topoisomerase: Types, Structure, Functions, …
2023年2月27日 · Topoisomerase is an essential enzyme that aids in the DNA replication process, segregation of chromosomes, transcription, and also in recombination. It was first found by J.C. Wang in the 1970s while working on …
Topoisomerase IV tracks behind the replication fork and the SeqA ...
2021年1月12日 · Topoisomerase IV (TopoIV) is a vital bacterial enzyme which disentangles newly replicated DNA and enables segregation of daughter chromosomes. In bacteria, DNA …
DNA gyrase and topoisomerase IV: biochemical activities
1998年10月1日 · DNA gyrase and topoisomerase IV are the two type II topoisomerases present in bacteria. Though clearly related, based on amino acid sequence similarity, they each play …
DNA Topoisomerase IV - an overview | ScienceDirect Topics
Topoisomerase IV is the most recently discovered E. coli topoisomerase and has a structure similar to DNA gyrase. These heterotetrameric enzymes are encoded by the genes parC and …
