2016年6月15日 · Uric acid production and metabolism are complex processes involving various factors that regulate hepatic production, as well as renal and gut excretion of this compound. …

Uric acid metabolism is done in the human gut by ∼1/5 of bacteria species that come from 4 of 6 major phyla. Such metabolism is anaerobic involving uncharacterized ammonia lyase, …

2016年6月15日 · Overproduction of uric acid, generated from the metabolism of purines, has been proven to play emerging roles in human disease. In fact the increase of serum uric acid …

Uric acid, C 5 H 4 N 4 O 3, 7,9-dihydro-1 H-purine-2,6,8 (3 H)-trione, molecular mass 168 Da, is a product of the metabolic breakdown of purine nucleotides (adenine and guanine). Crystals of …

The urinary excretion of uric acid is increased by the hormones of the adrenal cortex as well as by ACTH. Muscular exercise increases uric acid output. Variations of Uric Acid Excretion with …

2016年6月15日 · Uric acid production and metabolism are complex processes involving various factors that regulate hepatic production, as well as renal and gut excretion of this compound. …

Uric acid is the final product of purine metabolism and is converted to allantoin in most mammals via the uricase enzyme. The accumulation of loss of function mutations in the uricase gene …

Serum uric acid reflects the interactions of four major processes: dietary purine intake, endogenous purine metabolism, urinary urate excretion, and intestinal uricolysis. The typical …

2025年1月28日 · uric acid, a compound belonging to the purine group, and the chief form in which nitrogen, resulting from the breakdown of protein during digestion, is excreted by reptiles and …

2020年11月1日 · Uric acid (pKa 5.8) is a weak organic acid that exists at physiological pH as urate. Uric acid is produced primarily in the liver as the end product of exogenous and …