Alkylation is a chemical reaction that entails transfer of an alkyl group. The alkyl group may be transferred as an alkyl carbocation, a free radical, a carbanion, or a carbene (or their …

Alkylating agents are compounds that work by adding an alkyl group to the guanine base of the DNA molecule, preventing the strands of the double helix from linking as they should. This …

An alkylating antineoplastic agent is an alkylating agent used in cancer treatment that attaches an alkyl group (C n H 2n+1) to DNA. [1] Since cancer cells, in general, proliferate faster and with …

Alkylating agent, any highly reactive drug that binds to certain chemical groups (phosphate, amino, sulfhydryl, hydroxyl, and imidazole groups) commonly found in nucleic acids and other …

The meaning of ALKYLATION is the act or process of introducing one or more alkyl groups into a compound (as to increase octane number in a motor fuel).

Alkylation is the migration of an alkyl substituent from one molecule to another via an alkyl carbocation, a carbanion, a free radical, and a carbene, which are generated from electrophilic …

Alkylating agents are medications that are mainly used to treat cancer. They are effective against hematologic malignancies, such as leukemia, lymphoma, and multiple myeloma, as well as …

2024年5月21日 · Alkylation is the introduction of a hydrocarbon group onto a chemical. Hydrocarbons are molecules with a carbon atom bound to hydrogen atoms. Alkyl groups …

2015年3月10日 · Alkylating agents are a class of antineoplastic or anticancer drugs which act by inhibiting the transcription of DNA into RNA and thereby stopping the protein synthesis.

Alkylation is the process of introducing an alkyl group (a hydrocarbon chain) into a molecule, typically through the reaction of a nucleophile with an alkyl halide or other alkylating agent.