Leucine is a dietary amino acid with the capacity to directly stimulate myofibrillar muscle protein synthesis. [24] . This effect of leucine results from its role as an activator of the mechanistic target of rapamycin (mTOR), [8] a serine-threonine protein kinase that …

The meaning of LEUCYL is the amino acid radical or residue (CH3)2CHCH2CH (NH2)CO— of leucine —abbreviation Leu.

L- 亮氨酸 （L-Leucine）属必需氨基酸，化学式为C6H13NO2，与D-亮氨酸是对映异构体，室温下为白色有光泽六面体结晶或白色结晶性粉末。 无臭，略有苦味。 于145～148℃升华。 熔点293~295℃（分解）。 在烃类存在下，在无机酸水溶液中性能稳定。 微溶于乙醇（0.07%），溶于稀盐酸和碱性氢氧化物和碳酸盐溶液。 不溶于乙醚。 [1] L- 亮氨酸，1819年Proust首先从 奶酪 中分离得到。 后来，Braconnot从肌肉与羊毛的酸 水解 物中得到其结晶，并定名为 亮氨酸。 L- …

Leucyl-leucine | C12H24N2O3 | CID 94244 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

2019年11月28日 · We provide evidence for a role of leucyl-tRNA synthetase 1 (LARS1) in glucose-dependent control of leucine usage. Upon glucose starvation, LARS1 was phosphorylated by Unc-51 like autophagy activating kinase 1 …

Identified LAPs include human LAP, bovine lens LAP, porcine LAP, Escherichia coli (E. coli) LAP (also known as PepA or XerB), and the solanaceous -specific acidic LAP (LAP-A) in tomato (Solanum lycopersicum). LAP-A active site residues. Two Zn+2 cations are also shown, along with a water and a bicarbonate ion that acts as a general base.

2000年5月5日 · We describe the first crystal structure of a leucyl-tRNA synthetase, from the hyperthermophile Thermus thermophilus, at 2.0 Å resolution. The overall architecture is similar to that of isoleucyl-tRNA synthetase, except that the putative editing domain is inserted at a different position in the primary structure.

Leu-Leu is a dipeptide formed from two L-leucine residues. It has a role as a human metabolite and a Mycoplasma genitalium metabolite. It is functionally related to a L-leucine. It is a tautomer of a Leu-Leu zwitterion. Follow these links to do a live 2D search or do a live 3D search for this compound, sorted by annotation score.

leucyl (plural leucyls) (organic chemistry) The univalent radical derived from leucine.

2020年1月10日 · We provide evidence for a role of leucyl-tRNA synthetase 1 (LARS1) in glucose-dependent control of leucine usage. Upon glucose starvation, LARS1 was phosphorylated by Unc-51 like autophagy activating kinase 1 (ULK1) at the residues crucial for leucine binding.