In this review we describe the current state-of-art of mRNA vaccines, focusing on the challenges and bottlenecks of manufacturing that need to be addressed to turn this new vaccination technology into an effective, fast and cost-effective response to emerging health crises.

2023年7月5日 · What is mRNA Manufacturing? mRNA manufacturing involves the synthetic production of messenger RNA, a type of RNA that conveys genetic information from DNA to the machinery within cells responsible for protein synthesis. This process forms the basis of numerous biological functions, and harnessing it has opened up new avenues in biotechnology.

2022年4月1日 · The remarkable success of SARS CoV-2 mRNA-based vaccines and the ensuing interest in mRNA vaccines and therapeutics have highlighted the need for a scalable clinical-enabling manufacturing process to produce such products, and robust analytical methods to demonstrate safety, potency, and purity.

Find high-quality raw materials and products for mRNA manufacturing and formulation. Our mRNA and lipid CDMO service and testing services can help enable your fast turnaround times.

2022年3月3日 · To understand the current state of mRNA-LNP production, current methods and technologies are reviewed, as are current and announced global capacities for commercial manufacturing.

Accelerate your mRNA vaccine and therapeutics from preclinical development to commercialization with our comprehensive portfolio of products and services proven to help meet critical process, scale, quality, and regulatory needs.

2024年10月30日 · mRNA vaccines have revolutionised the fight against infectious diseases, offering rapid production and strong immune responses. But how are they made, and what about safety concerns? Let’s break down the process.

2024年5月30日 · Messenger RNA, or mRNA, carries instructions that cells use to make proteins. Scientists have studied mRNA for decades, but its use in developing successful COVID-19 vaccines has spawned great interest in mRNA technology, not only for use in vaccines, but also mRNA-based therapeutics.

Learn how a broad portfolio of high-quality products coupled with the right analytics and testing strategy assures success in mRNA production. High-quality excipients, custom and portfolio lipid options, single-use solutions, and tailored services support the formulation of …

2022年9月13日 · The mRNA manufacturing process is made up of discrete, specialized steps. In theory, biotechnology developers could outsource every step to a different manufacturing partner, each with different pricing, capacities and specialized knowledge. However, this “divide-and-conquer” strategy requires developers to coordinate between multiple ...