2023年7月24日 · Pathologic elevation of conjugated or direct bilirubin (concentration higher than 2 mg/dL or more than 20% of total bilirubin) is termed conjugated hyperbilirubinemia. It is a biochemical marker of cholestasis and hepatocellular dysfunction. [1]

2023年9月19日 · Conjugated bilirubin is otherwise also known as direct bilirubin. Conjugated bilirubin is water soluble and is not toxic to the body. An adult's normal value of conjugated bilirubin should be between 0.0 to 0.3 mg/dL. Since conjugated bilirubin is water soluble, it can be filtered by the kidney.

2023年1月9日 · “Conjugated” bilirubin is the bilirubin your liver processed. Sometimes it’s called “direct” bilirubin on your test results. That’s because this type can be measured directly.

2023年9月26日 · Conjugated ("direct") bilirubin. This is the bilirubin once it reaches the liver and undergoes a chemical change. It moves to the intestines before being removed through your stool.

2023年2月25日 · Investigations and analysis of conjugated bilirubin, unconjugated bilirubin, urobilinogen and bilirubinuria.

Conjugated hyperbilirubinemia is a medical condition that refers to the buildup of bilirubin in the bloodstream, specifically the conjugated form. This condition can be indicative of underlying liver or bile duct issues.

In the liver, uridine diphosphate (UDP)-glucuronyl transferase (UGT) converts bilirubin to a mixture of monoglucuronides and diglucuronides, referred to as conjugated bilirubin, which...

2023年7月24日 · Pathologic elevation of conjugated or direct bilirubin (concentration higher than 2 mg/dL or more than 20% of total bilirubin) is termed conjugated hyperbilirubinemia. It is a biochemical marker of cholestasis and hepatocellular dysfunction. Approximately 80% of the bilirubin is derived from hemoglobin metabolism.

2018年1月1日 · Conjugated or direct hyperbilirubinaemia occurs when the the liver is able to conjugate bilirubin, but the excretion is impaired. Causes include: The proportion of conjugated bilirubin with respect to the total raised bilirubin can give a clue as to cause of jaundice. 20-40% of total: more suggestive of hepatic than posthepatic jaundice.

Direct bilirubin correlates with conjugated bilirubin but tends to overestimate actual conjugated bilirubin, as it includes both the conjugated bilirubin and bilirubin covalently bound to...